منابع مشابه
Hapmap flap
Two years ago, when biologists declared victory in sequencing the human genome, the announcement seemed all the more believable because the president of the United States himself was there to share the glory. Two years later, cancer has still not been cured, the major genetic causes of diabetes have not been uncovered, and truth be told, the human genome has still not really been fully sequence...
متن کاملNavigating the HapMap
With the availability of the HapMap--a resource which describes common patterns of linkage disequilibrium (LD) in four different human population samples, we now have a powerful tool to help dissect the role of genetic variation in the biology of the genome. HapMap is entirely complimentary to the human genome map and so it is particularly fitting that it should be viewed in a full genomic cont...
متن کاملThe International HapMap Project
The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain. An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association...
متن کاملThe hapmap project : Nature
| Full Text | PDF (1,269K) | Supplementary information http://www.nature.com/nature/journal/v437/n7063/edsumm/e051027-01.html (1 of 2)12/30/2005 6:56:22 AM The hapmap project : Nature
متن کاملInterchromosomal LD in HapMap Genotypes
Then, using all of these tags were used to calculate intrachromosomal LD within each panel. Analysis was done using an EM algorithm based on code from Goncalo Abecasis. Marker pairs with r2 0.6 were stored for further analysis. As shown in Table 2, the number of distinct pairs of SNPs with r2 0.6 and 0.8 are shown. The numbers are shown for the original tag set. Additionally, to facilitate cros...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Methods
سال: 2010
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth1010-780b